7-Deaza-2'-Deoxyguanosine 5'-Triphosphate, 5 mM solution (c⁷dGTP), 2 umol-CYTIVA 27209002

For reducing band compressions* in sequencing gels. Supplied as convenient solutions at pH 7.0 and 7.5. c⁷dGTP is supplied in purified water as 5 mM and 10 mM solutions. Band compressions are ambiguous band patterns on sequencing gels caused by stable intrastrand secondary structures that are not fully denatured during electrophoresis. Their occurrence can be reduced by substituting nucleotide analogs in the sequencing mixes. To resolve Gband compressions, use 7deaza dGTP (c⁷dGTP).