High yields achieved through the highresolution beads and selectivity of the ligand. Efficient removal of aggregates, viruses, and main contaminants in MAb processes. 1NA cm bed height of HiScreen columns allows method optimization and parameter screening. Reproducible results, scalable to BioProcess columns packed with the same chromatography media using the same linear fluid velocity. The multimodal functionality of Capto adhere ImpRes gives a different selectivity compared with traditional ion exchange columns and it binds proteins at high or low ionic strength. Contaminants such as DNA, host cell proteins (HCP), leached protein A, aggregates, and viruses are efficiently removed, making Capto adhere ImpRes an excellent choice for purification of MAbs and other biomolecules with high aggregate content. Capto adhere ImpRes is designed to allow effective, highresolution polishing of MAb in the second or third step of a purification scheme downstream of the protein A capture step.
