The alkalitolerant recombinant protein A ligand of MabSelect Sure LX allows cleaninginplace (CIP) and the medium gives increased binding capacity. Prepacked, ready to use columns for convenient process development. 1NA cm bed height of HiScreen columns is designed to allow method optimization and parameter screening. Easily connected in series to achieve 2NA cm bed height. Small bed volume gives fast results and minimal sample/buffer consumption. Reproducible results, scalable to BioProcess columns packed with the same chromatography media using the same linear fluid velocity. The small column volume of 4.7 ml and bed height of 1NA cm make HiScreen columns excellent tools for method optimization, parameter screening, robustness testing, and convenient scaleup. Process fluid velocities can be applied, since the 1NA cm bed height If necessary, two columns can easily be connected in series to give a bed height of 2NA cm. Media prepacked in HiScreen MabSelect SuRe LX columns are also available in other formats and as bulk packs, which makes it possible to use the same media for development work, pilot studies, and routine production.
