Convenient prepacked column for fast, reproducible, and easy small scale purifications. High binding capacity, > 100 mg MAb/mL resin. Efficient aggregate removal at high load of monoclonal antibodies. Highresolution intermediate purification and polishing based on the wellestablished Capto platform. Flexibility of design thanks to a large operational window of flow rates and bed heights for easy optimization and scaling. HiTrap Capto S ImpAct columns are prepacked with Capto S ImpAct cation exchange chromatography resin for screening and small scale protein purifications using ion exchange chromatography (IEX). HiTrap Capto S ImpAct (1 mL and 5 mL) are prepacked columns for small scale purifications, as well as optimization of methods and parameters, such as sample load and binding conditions. HiTrap Capto S ImpAct columns provide fast, reproducible and easy separations in a convenient format. The columns are best utilized when they are connected to liquid chromatography systems such as ÄKTA systems.