Convenient and affordable for fast, easy ion exchange separations either alone or connected in series. The industry standard for ion exchange chromatography. High flow rates and good scaleup potential. Use a weak ion exchanger if the selectivity of a strong ion exchanger is insufficient. Predictable scaleup Q, SP, DEAE, and CM Sepharose Fast Flow are based on a robust, 6% highly crosslinked beaded agarose matrix with good flow properties and high loading capacities. ANX Sepharose 4 Fast Flow (high sub) is based on 4% highly crosslinked beaded agarose. This results in a medium with higher porosity, which is particularly useful for the purification of high molecular mass proteins.