Higher dynamic binding capacity than currently available Protein A chromatography media. Improved process economics through reduced raw materials costs and/or reduced number of cycles High purity capture due to high ligand selectivity and matrix hydrophilicity Slightly lower pressure/flow properties compared to MabSelect SuRe and MabSelect. MabSelect Xtra has the same recombinant Protein A ligand as MabSelect but is based on a highflow agarose base matrix with increased porosity and a slightly decreased particle size compared to MabSelect. This results in higher capacity—MabSelect Xtra has about 3NA% higher dynamic binding capacity for IgG than currently available Protein A chromatography media In addition, MabSelect Xtra has a higher capacitiy for many Fcfusion proteins. The medium provides a lower overall production cost due to the possibility of processing concentrated feedstocks in fewer batches MabSelect Xtra is available in a range of different bulk pack sizes and convenient prepacked formats for easy scaleup and process development.
As member of the BioProcess media range, MabSelect Xtra meets industrial demands with security of supply and comprehensive technical and regulatory support.
