Sera-Mag™ Carboxylate-Modified [E3] Magnetic Particles, 15 mL-CYTIVA 44152105050250

Wide application range: Carboxylic groups on the surface form covalent amide bonds with proteins, peptides or aminemodified ligands for use in many downstream applications including protein purification, DNA sample preparation and Clean-Up, protenomicsand immunoassays. Convenient One step or twostep coupling: Carbodiimide chemistry allows rapid formation of stable bonds to minimize ligand leaching. Fast magnetic separation: Available in original SeraMag™ format or SeraMag™ SpeedBeads version for faster magnetic response and shorter assay times in clinical diagnostic tests. High performance: Excellent sensitivity and low nonspecific binding for greater accuracy. SeraMag™ SpeedBeads™ and SeraMag™ CarboxylateModified Magnetic Particles combine a fast magnetic response time and high binding capacity with a large surface area, high sensitivity, stability, physical integrity, and fast reaction kinetics. Covalent coupling of biomolecules such as proteins and nucleic acids to carboxyl groups on the surface is easily accomplished using our standard coupling technology. Typical applications include sample preparation, proteomics, nucleic acid isolation, and immunoassay applications. Fast Magnetic Response Times and Stable Physical Integrity The core of the particle is made by a free radical emulsion polymerization of styrene and acid monomer. One (SeraMag™) or two (SeraMag™ SpeedBeads™) layers of magnetite are then coated onto this core, while the surface is modified to minimize nonspecific binding of proteins.