Binds and elutes relatively strong hydrophobic molecules at comparatively low salt concentrations The least hydrophobic medium in the well proven Sepharose Fast Flow HIC range Purifies recombinant Hepatitis B virus surface antigen from CHO cells Developed and optimized in cooperation with a processscale manufacturer of biopharmaceuticals The hydrophilic nature of the base matrix ensures low levels of nonspecific binding. ButylS Sepharose 6 Fast Flow is part of the Sepharose Fast Flow HIC platform, which has been an industrial standard for HIC chromatography during recent decades. ButylS Sepharose 6 Fast Flow is composed of crosslinked 6% agarose beads modified with butyl groups via a thioether linkage. It will exhibit a different selectivity compared to Butyl Sepharose 4 Fast Flow and other HIC Sepharose Fast Flow products. This resin is designed for the binding and elution of relatively strong hydrophobic molecules at comparatively low salt concentrations. Butyl‑S Sepharose 6 Fast Flow is particularly useful during the initial stages of a separation process to remove the bulk of impurities without stringent requirements for conditioning of the sample (e.g. adjustment of pH, salt concentration etc.) ButylS Sepharose 6 Fast Flow is available in a range of different bulk pack sizes and convenient prepacked formats for easy scaleup and process development.
As member of the BioProcess media range, ButylS Sepharose 6 Fast Flow meets industrial demands with security of supply and comprehensive technical and regulatory support
