Whatman Polydisc 50 mm in-line disc filters are designed for larger volume sample filtration in the laboratory, at a pilot plant or in manufacturing. They are extremely versatile and cost effective. Sample volumes up to 1 liter can be filtered with one device. Polydisc devices can be used in conjunction with a syringe or connected in-line (6-10 mm ID hose) via stepped hose barbs. The Polydisc AS (Aqueous Solution) family of 50 mm filter devices features a high throughput polyethersulfone membrane, which has low protein binding and no surfactants, developed for use in the pharmaceutical industry. A glass microfiber prefilter extends the life of the membrane and effectively filters heavily contaminated samples. Each Polydisc AS device has a sterility cap on the outlet and is sealed in its own "medical grade" clear blister pack, radiation sterilized and secured in a protective shelf pack. Applications include tissue culture media, reagent preparation, particle counting solutions and pharmaceutical preparations.